![]() ![]() ![]() dioica did not exhibit the inhibition effect on PON1. However, methanol and water extracts of the U. dioica exhibited significant inhibition on the AChE (IC50= 0.098 ± 0.011 mg/mL). +), ferric reducing antioxidant power (FRAP), and cupric ion reducing antioxidant capacity (CUPRAC) methods.+), 2,2-diphenyl-1-picrylhydrazyl (DPPH.dioica extracts (methanol, hexane, and water) was determined by applying 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS Phytochemical content was determined by the liquid chromatography/mass spectrometry (LC-MS/MS), and to assess the enzyme inhibition and antioxidant capacity the spectrophotometer technique was used. This plays a role in the regulation of HDL and LDL and an antiatherogenic, and antioxidant capacity of Urtica dioica. This study aimed to investigate the phytochemical content and the inhibition effect on acetylcholinesterase (AChE), which interact with beta-amyloid to promote the deposition of amyloid plaques and paraoxonase (PON1). dioica is an annual or perennial herbaceous plant belonging to the Urticaceae family that has an important place in ethnobotany.
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